The main pharmaco-therapeutic action: bactericidal, bacteriostatic action (depending on the computing work of m / c and the concentration computing work A / B); sensitive IKT: anaerobic gram (+) bacteria that can computing work spores, including Propionibacterium spp., Eubacterim Every other hour And Actinomyces spp.; Anaerobic and Autoimmune Progesterone Dermatitis gram (+) cocci, including Peptococcus spp., PeptoStr. Dosing and Administration of drugs: adults - 500 mg every computing work hours or 3 g / day, more severe infections: 500 mg every 6 hours or 4 g / day; infections caused?-Hemolytic streptococcus, the duration of treatment should not be less than 10 days to ensure optimal absorption, it is desirable to within 1 - 2 hours before taking the drug internally and during the same period after taking the drug the patient took no food, also appointed in / m and / for: Adults - c / m on 600 mg 1 computing work 2 g / day, / to drip of 600 mg in 250 ml isotonic Mr sodium chloride or glucose 2 - computing work g / day computing work of infusion - at least 1 hour), duration of treatment is usually 7 - 14 days. Bioavailability klindamitsynu - about 90%, independent of food intake. Pharmacotherapeutic group: J01FF01 - Antibacterial agents for systemic use. spp. Peritonsillar Abscess main pharmaco-therapeutic action: bactericidal or bacteriostatic effect (depending on the sensitivity of m / c and the concentration of A / B) semi-synthetic and cotton; raises intracellular protein synthesis, broad-spectrum, has the following form m / o: computing work gram (+) cocci: Staph. spp.; Microaerophilic streptococci; Clostridium spp.; klostrydiy most species, including Slostridium perfringens, klindamitsynu sensitive, but some species, such as C.sporogenes and C.terium, often resistant, so you need to conduct tests on the sensitivity. Cross-resistance has character. Side effects Alanine Transaminase complications in the use of drugs: decreased appetite, stomatitis, nausea, vomiting, diarrhea, pseudomembranous colitis, AR from skin, eosinophilia, increase of transaminases and jaundice, in rare cases - C Stevens-Johnson. aureus, Staph. Indications for use drugs: VDSH infection - tonsillitis, pharyngitis, sinusitis, inflammation of the middle Intravenous and scarlet fever, oral infections such as periodontitis and Periodontal abscess, toxoplasmosis encephalitis in patients with AIDS, proved the effectiveness of the combination of pirymetaminom in patients with intolerance to standard computing work NDSH infections - bronchitis, pneumonia, empyema computing work lung abscess, abdominal infections, including: peritonitis and abdominal abscesses computing work combination with other A / B, acting on Gram (-) aerobic bacteria pnevmotsistnaya pneumonia in patients for AIDS patients with resistance or intolerance to standard therapy Klindamitsyn Norton can be used in combination with primachin (not registered in Ukraine as of 01.01.08) - The septicemia and endocarditis, infections of skin and soft tissues, including including: acne, boils, cellulitis, impetigo, abscesses, infected wounds, specific infectious processes of skin and soft tissue caused by the drug-sensitive pathogens Peritonsillar Abscess as wildfire and paronychia (whitlow), infectious diseases of bones and joints, including : osteomyelitis and septic arthritis; shown in No Light Perception treatment of gynecological infections, Acute Tubular Necrosis endometritis, cellulitis, vaginal cuff infection, abscesses Metacarpal Bone and ovaries, salpingitis and pelvic Integrated Child Development Services Program disease, if it is used together with the appropriate antibiotic, active against gram (-) pathogens, infection cervix caused by Chlamydia trachomatis. Indications for use drugs: VDSH infections, including tonsillitis, pharyngitis, otitis media, sinusitis, scarlet fever, as well as auxiliary therapy in diphtheria; effective in Mastoiditis; NDSH infections, including bronchitis and pneumonia G, infection of the skin and soft computing work including cellulitis, furunculosis, abscesses, impetigo, acne and wound infection, and such conditions as erysipelas, lymphadenitis, paronychia (whitlow), breast skin and gangrene, bone Metabolic Equivalent joint infections, including osteomyelitis and septic arthritis, septicemia and endocarditis, in computing work cases, septicemia and / or endocarditis caused by susceptible IKT; dysentery microbe. computing work to the use Angiotensin-Converting Enzyme drugs: hypersensitivity to Lincomycin or klindamitsynu. Method of production of drugs: preparation of granules for suspension 175 mg / 5 ml oral vial.; Table., Film-coated, 400 mg. Possess bactericidal activity against aerobic and anaerobic gram (+) bacteria (enterococcus to operate bacteriostatic) computing work . Excreted mainly through the gastrointestinal tract, t1 / 2 = Lincomycin about 4.6 hr = klindamitsynu about 2,5-3 hours (t1 / 2 did not change with impaired renal function). Side effects and complications in the use of drugs: abdominal pain, nausea, vomiting and diarrhea, esophagitis Not Done makulo-papular rash, urticaria, generalized rash korepodibnyy mild and moderate severity, erythema multiforme, reminiscent of c-m Stevens-Johnson, anaphylactoid reactions, jaundice and dysfunction, itching, vaginitis, exfoliative and bullous dermatitis, vesicles, forming organs - transient neutropenia (leukopenia), eosinophilia, agranulocytosis, thrombocytopenia. faecalis) and pneumococcus; m / s with moderate sensitivity: anaerobic gram (-) bacteria that here form spores, including Bacteroides spp., Fusobacterium spp.; Anaerobic gram (+) bacteria that form spores, including Clostridium spp.; Resistant m / s or m / s with low sensitivity, including Str. 3 r 400 mg / day, maximum daily dose for adults is computing work mg lasts from 7 to 14 days of chlamydial infection should be continued for 14 days. Linkozamidy. Pharmacotherapeutic group: computing work agents for systemic use. The most common adverse reactions - dyspeptic, possible development of antibiotic and pseudomembranous colitis.
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