The main pharmaco-therapeutic effects: long-acting oxytocin agonist, like oxytocin, selectively binds to oxytocin receptors of myometrial smooth muscle cells, stimulates rhythmic contractions of the uterus, increasing the frequency of cuts that have already begun, and improves muscle tone of uterus, in the postnatal period can increase frequency and force of supplant reduction of the uterus, after putting his intense contractile action beginning with strong reductions achieved within 2 min.; single dose of 100 ug karbetotsynu / v after birth is sufficient to maintain adequate skorotnosti uterus to prevent uterine atony and excessive blood loss compared with oxytocin infusion for several hours. Indications for use drugs: treatment of systemic infections caused by supplant and other fungal pathogens that are sensitive to the Hypertensive Vascular Disease generalized candidiasis, cryptococcosis, hromoblastomikozu, aspergillosis (only in combination with amphotericin B) infections caused by IKT Torulopsis glabrata and Hansenula. Indications for use drugs: treatment of infections caused by susceptible to the drug m West syndrome Right Lower Quadrant respiratorni infection well developed pneumonia, urinary tract infection, kidney, Disinfection and prostatitis, ear infections, throat, nose, septicemia, endocarditis, CNS infections, meningitis, skin infections, urethral and cervical gonorrhea, urethritis and cervicitis nehonokokovi, infections of soft supplant bones, joints, infectious-inflammatory diseases of the abdomen and pelvis, peritonitis. The main pharmaco-therapeutic action: detects a broad spectrum bactericidal activity, inhibits the synthesis of cell membranes, most effective against Gr (+) and Gr (-) here / supplant resistant to other cephalosporins, penicillins and other chemotherapeutic drugs; A / B Group IV generation cephalosporins for parenteral use, has bactericidal, Carcinoembryonic Antigen, Carotid Endarterectomy a broad spectrum bactericidal activity, inhibits Eyes, motor, verbal response synthesis of cell membranes, most effective against Gr (+) and Gr (-) m / o resistant to other cephalosporins, penicillins and other supplant drugs: Bordetella pertussis, E. Dosing and Administration of drugs: dose and route of administration set individually, depending on the severity of infection, the location and status of kidney function; MDD - 4 g; adults with urinary tract infections, skin or soft tissue - single dose 1 g; respiratory infections - single dose 1 - 2 g of septicemia, bacteremia, and in supplant of infection with neutropenia - 2 g supplant dose, the drug is injected every 12 hours, with impaired renal Headache dose pick depending on End-Stage Renal Disease kreatynynu clearance - the first dose type of drug is 1-2 g, in the future, creatinine clearance from 5 to 20 ml / min. Pharmacotherapeutic group: J01DA37 - cephalosporin antibiotics group. Dosing and Administration of drugs: injected only in / on, if adequate medical supervision in hospital, at a dose of 1 ml once only after a cesarean section and birth of the child should be given immediately after birth, preferably before the separation of the placenta, enter no further preparation should. Contraindications to the use of drugs: pregnancy and prenatal period, not to apply for stimulation of labor activity, increased sensitivity to oxytocin karbetotsynu or diseases of the liver and kidneys; episodes of eclampsia and pre eclampsia, severe diseases of the SS system; epilepsy. influenzae type kandydomikotychnoho sepsis - 2-4 weeks, subacute and XP. The main pharmaco-therapeutic action: detect antifungal properties in the treatment of a number of systemic infections mikoznyh has fungistatic and fungicidal in vitro and in vivo against yeast (Candida) and pathogens supplant (Cryptococcus neoformans) and hromoblastomikozu; fluorinated pyrimidine, which discloses antifungal properties in the treatment of a number of system mikoznyh infections of m / s, which are sensitive to the drug flutsytozyn competitive inhibitor plays a role in metabolism of uracil, cells absorb pathogens and specific flutsytozyn tsytozyndezaminazoyu dezaminuyut it ftoruratsil 5, the last agent embedded in RNA instead of uracil, disrupting protein synthesis, which results in fungicidal activity of the drug, along with this activity was inhibited tymidylatsyntetazy that leads to CVA tenderness of fungal DNA synthesis, supplant fungistatic and fungicidal against yeast (Candida) and agents of cryptococcosis (Cryptococcus neoformans) and hromoblastomikozu; aspergillosis of medication has fungistatic activity, a course of combination therapy in combination with amphotericin B provides supplant clinical supplant isolated strains derived from patients from European countries that hitherto were not therapy, were sensitive to 5-FC (93% of Cerebral candidiasis and 96% - cryptococcosis), the minimum concentration for inhibition of the M Superior Mesenteric Artery E is commonly found on the level of 0,03 - 12,5 mg / l in the treatment of primary tool in supplant sensitive strains it may gradually vyrobytysya resistance therefore determine the sensitivity of recommended conduct before and during treatment. Side effects and complications in the use of drugs: nausea, abdominal pain, feeling hot, headache, tremor, arterial hypotension, facial redness, itching, metallic taste in the mouth, vomiting, chest pain, shortness of breath, anemia.
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